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The last steps of alcoholic fermentation in bacteria, plants, and yeast involve the conversion of pyruvate into acetaldehyde and carbon dioxide by the enzyme pyruvate decarboxylase, followed by the conversion of acetaldehyde into ethanol. The latter reaction is again catalyzed by an alcohol dehydrogenase, now operating in the opposite direction.
The reinforcing effects of alcohol consumption are mediated by acetaldehyde generated by catalase and other oxidizing enzymes such as cytochrome P-4502E1 in the brain. [60] Although acetaldehyde has been associated with some of the adverse and toxic effects of ethanol, it appears to play a central role in the activation of the mesolimbic ...
Neutral spirit is legally defined as spirit distilled from any material distilled at or above 95% ABV (190 US proof) and bottled at or above 40% ABV. [5] When the term is used in an informal context rather than as a term of U.S. law, any distilled spirit of high alcohol purity (e.g., 170 proof or higher) that does not contain added flavoring may be referred to as neutral alcohol. [13]
Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula CH 3 CH 2 OH. It is an alcohol, with its formula also written as C 2 H 5 OH, C 2 H 6 O or EtOH, where Et stands for ethyl. Ethanol is a volatile, flammable, colorless liquid with a characteristic wine-like ...
Soon after ingestion, it begins to be metabolized, 90% or more by the liver. One standard drink is sufficient to almost completely saturate the liver's capacity to metabolize alcohol. The main metabolite is acetaldehyde, a toxic carcinogen. Acetaldehyde is then further metabolized into ionic acetate by the enzyme aldehyde dehydrogenase (ALDH).
Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent.
Cetyl alcohol / ˈ s iː t əl /, also known as hexadecan-1-ol and palmityl alcohol, is a C-16 fatty alcohol with the formula CH 3 (CH 2) 15 OH. At room temperature, cetyl alcohol takes the form of a waxy white solid or flakes. The name cetyl refers to whale oil (cetacea oil, from Latin: cetus, lit.
The International Agency for Research on Cancer lists ethanol as a carcinogen and states that: "There is sufficient evidence and research showing the carcinogenicity of acetaldehyde (the major metabolite of ethanol) which is excreted by the liver enzyme when one drinks alcohol." [95] The World Health Organization also considers alcohol to be a ...