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The focus of translational neuroscience research is to investigate the molecular mechanisms for these disorders, and to investigate the mechanisms of drug delivery to treat these disorders, including an investigation into the impact of the blood-brain barrier on drug delivery, and the role of the body's immune system in neurodegenerative disorders.
The Journal of Neural Transmission is a monthly peer-reviewed medical journal covering clinical neurology and translational neuroscience. It was established in 1950 by Carmen Coronini and Alexander Sturm as Acta Neurovegetativa. [1] It was renamed to the Journal of Neuro-Visceral Relations in 1968 and to its current title in 1972.
In bioscience, translational research is a term often used interchangeably with translational medicine or translational science or bench to bedside. The adjective "translational" refers to the " translation " (the term derives from the Latin for "carrying over") of basic scientific findings in a laboratory setting into potential treatments for ...
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. [1] [2] [3] It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand ...
Karen Faith Berman is an American psychiatrist and physician-scientist who is a senior investigator and chief of the section on integrative neuroimaging, the psychosis and cognitive studies section, and the clinical and translational neuroscience branch of the National Institute of Mental Health's division of intramural research.
The following outline is provided as an overview of and topical guide to neuroscience: Neuroscience is the scientific study of the structure and function of the nervous system. [ 1 ] [ 2 ] It encompasses the branch of biology [ 3 ] that deals with the anatomy , biochemistry , molecular biology , and physiology of neurons and neural circuits .
Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...
In certain cases one of these steps (i.e., nuclear import or nuclear export) is regulated, often by post-translational modifications. Nuclear import limits the propagation of large proteins expressed in skeletal muscle fibers and possibly other syncytial tissues, maintaining localized gene expression in certain nuclei. [ 7 ]