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Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
Progress continued in 1999 when the first artificial organ made using bioprinting was printed by a team of scientist leads by Dr. Anthony Atala at the Wake Forest Institute for Regenerative Medicine. [8] The scientists at Wake Forest printed an artificial scaffold for a human bladder and then seeded the scaffold with cells from their patient. [5]
Stephen F. Badylak pioneered the process of decellularization at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh. [2] This process creates a natural biomaterial to act as a scaffold for cell growth, differentiation and tissue development. By recellularizing an ECM scaffold with a patient’s own cells, the ...
Biomedical Materials is a peer-reviewed medical journal that covers research on tissue engineering and regenerative medicine. The editors-in-chief are Myron Spector (Harvard Medical School and VA Boston Healthcare System) and Joyce Wong (Boston University).
Nano-scaffolding or nanoscaffolding is a medical process used to regrow tissue and bone, including limbs and organs. The nano-scaffold is a three-dimensional structure composed of polymer fibers very small that are scaled from a Nanometer (10 −9 m) scale. [1]
In 2007, Christman joined the Department of Bioengineering at UCSF. She develops materials for tissue engineering and regenerative medicine. Her research considers naturally-occurring and synthetically derived hydrogels to repair and regenerate tissue. [4] She looks to use these hydrogels for non-invasive therapeutic interventions. [4]
Although synthetic materials have been shown to achieve cell infiltration and nerve regeneration, preclinical data demonstrate that such materials are positive for smooth muscle actin staining, which indicates activated myofibroblasts and the potential for scarring. [24] NFB develops scaffolds and scaffold-free approaches for cornea regeneration.
The Journal of Stem Cells & Regenerative Medicine is an open-access online scientific journal. It is the official journal of the German Society for Stem Cell Research (GSZ) and publishes research articles focusing on stem cells and regenerative medicine and related fields.