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Fetal warfarin syndrome is a disorder of the embryo which occurs in a child whose mother took the medication warfarin (brand name: Coumadin) during pregnancy. Resulting abnormalities include low birth weight , slower growth , intellectual disability , deafness , small head size , and malformed bones , cartilage , and joints .
However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
Warfarin is contraindicated in pregnancy, as it passes through the placental barrier and may cause bleeding in the fetus; warfarin use during pregnancy is commonly associated with spontaneous abortion, stillbirth, neonatal death, and preterm birth. [42]
Treatment of this condition is very similar to treatment of non-gravid heart failure patients, however, safety of the fetus must be prioritized. For example, for anticoagulation due to increased risk for thromboembolism, low molecular weight heparin which is safe for use during pregnancy is used instead of warfarin which crosses the placenta. [37]
Young mothers face higher risks of complications and death during pregnancy than older mothers, [30] especially adolescents aged 15 years or younger. [31] Adolescents have higher risks for postpartum hemorrhage, endometritis , operative vaginal delivery , episiotomy , low birth weight , preterm delivery , and small-for-gestational-age infants ...
New guidelines set by the American College of Obstetricians and Gynecologists emphasize that pregnancy risks should be characterized in five-year age groups—like ages 35–40, 40–44, et cetera ...
Acetaminophen has long been considered safe to help reduce fever and relieve pain while pregnant. Here's what experts say about new claims.
Teenage pregnancy, also known as adolescent pregnancy, is pregnancy in a female under the age of 20. [5] Worldwide, pregnancy complications are the leading cause of death for women and girls 15 to 19 years old. [3] The definition of teenage pregnancy includes those who are legally considered adults in their country. [2]
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