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Myb genes are part of a large gene family of transcription factors found in animals and plants. In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper. [5] [6] Members of the extended SANT/Myb family also include the SANT domain and other similar all-helical homeobox-like domains.
4605 17865 Ensembl ENSG00000101057 ENSMUSG00000017861 UniProt P10244 P48972 RefSeq (mRNA) NM_002466 NM_001278610 NM_008652 RefSeq (protein) NP_001265539 NP_002457 NP_032678 Location (UCSC) Chr 20: 43.67 – 43.72 Mb Chr 2: 162.9 – 162.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene. Function The ...
17864 Ensembl ENSG00000185697 ENSMUSG00000025912 UniProt P10243 P51960 RefSeq (mRNA) NM_001080416 NM_001144755 NM_001294282 NM_001290397 NM_008651 RefSeq (protein) NP_001073885 NP_001138227 NP_001281211 NP_001277326 NP_032677 Location (UCSC) Chr 8: 66.56 – 66.61 Mb Chr 1: 9.74 – 9.77 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MYB proto-oncogene like 1 is a protein that in ...
The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level [citation needed], and this region influences erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal ...
10514 18432 Ensembl ENSG00000132382 ENSMUSG00000040463 UniProt Q9BQG0 Q7TPV4 RefSeq (mRNA) NM_001105538 NM_014520 NM_016776 RefSeq (protein) NP_001099008 NP_055335 NP_058056 Location (UCSC) Chr 17: 4.54 – 4.56 Mb Chr 11: 72.33 – 72.34 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myb-binding protein 1A is a protein that in humans is encoded by the MYBBP1A gene. References ^ a b ...
The Myb domain (InterPro: IPR017930) acts by binding to double-stranded telomeric DNA. This region gets its name from a viral protein called Myb derived from the avian myeloblastosis virus. Specifically, the sequence that this Myb domain targets on the DNA is (GGTTAG/CCAATC)n.
MYB may refer to: MYB (gene), a human gene; Myb, a plant transcription factor family; Marylebone station, London, by National Rail station code; Mbay language, by ISO 639-3 code; MyB, South Korean girl group
The KIX domain contains two separate binding sites: the "c-Myb site", named after the oncoprotein c-Myb, and the "MLL site", named after the proto-oncogene MLL (Mixed Lineage Leukemia, KMT2A). [ 3 ] The paralogous coactivators CBP ( CREBBP ) and P300 ( EP300 ) are recruited to DNA -bound transcription factors to activate transcription.