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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
• Heart disease: Postmenopausal women are much more vulnerable to heart disease and stroke than premenopausal women. That’s because in a woman’s younger years, estrogen protects her heart.
Most women going through menopause now grew up in an era when the condition was still considered “rare,” and the signs and symptoms might have been brushed off as simply “cutting weight ...
High doses of norethisterone and noretynodrel have been associated with estrogenic side effects such as breast enlargement in women and gynecomastia in men, but also with alleviation of menopausal symptoms in postmenopausal women. [252] In contrast, non-estrogenic progestins were not found to be associated with such effects. [252]
Side effects of CEEs include breast tenderness and enlargement, headache, fluid retention, and nausea among others. [4] [1] It may increase the risk of endometrial hyperplasia and endometrial cancer in women with an intact uterus if it is not taken together with a progestogen like progesterone.
Additionally, data suggests that, after menopause, hair loss can also accelerate. A 2022 study of 178 postmenopausal women found that more than half of them experience female-pattern hair loss ...
The most common side effects reported by more than 2% of clinical trials subjects are hypercalciuria, dizziness, nausea, headache, palpitations, fatigue, upper abdominal pain and vertigo. [ 2 ] Preclinical studies revealed that abaloparatide systemic daily administration leads to a dose- and time-dependent increase in the incidence of ...
Menopause, which marks the end of a woman’s reproductive life, is something roughly half of the world’s population will go through if they live long enough. But it — like so much surrounding ...
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