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Anaplastic thyroid cancer. This rare type of thyroid cancer grows quickly and can be difficult to treat. However, treatments can help slow the progression of the disease. Anaplastic thyroid cancer tends to occur in people older than 60.
Different types of thyroid cancer have different sets of stages. For instance, medullary and anaplastic thyroid cancers each have their own set of stages. Differentiated thyroid cancer types, including papillary, follicular, Hurthle cell and poorly differentiated, share a set of stages.
Anaplastic thyroid cancer is one of the most aggressive and fastest-growing types of cancer. It can grow and spread rapidly in a matter of weeks. About 50% of people with ATC have metastasis (cancer spread) in distant areas of their body at diagnosis.
Anaplastic thyroid carcinoma is generally lethal, and 56% of patients have lymph-node metastases and 38% distant metastases at presentation. 2 The tumors are highly infiltrative, often have extrathyroidal growth, angiolymphatic invasion, and high-grade nuclear features.
JACKSONVILLE, Fla. — A combination of therapies may prove to be a promising advance for the treatment of anaplastic thyroid cancer based on results of a phase I clinical trial, say researchers at Mayo Clinic in Florida. Anaplastic thyroid cancer is one of the deadliest of all cancers.
Mayo Clinic thyroid cancer research includes investigations into common types of the disease, such as papillary thyroid cancer, and rare types of thyroid cancer, such as anaplastic thyroid cancer. Cancer research is conducted in coordination with the Mayo Clinic Comprehensive Cancer Center.
This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread.