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Goodman & Gilman's The Pharmacological Basis of Therapeutics, commonly referred to as the Blue Bible or Goodman & Gilman, is a textbook of pharmacology originally authored by Louis S. Goodman and Alfred Gilman. First published in 1941, the book is in its 14th edition (as of 2022), and has the reputation of being the "bible of pharmacology".
Limbird is the author of Cell Surface Receptors: A Short Course in Theory and Methods (1985, 1996, 2004); co-editor with Joel Hardman of the 9th (1995) and 10th (2001) editions of Goodman and Gilman’s Pharmacological Basis of Therapeutics; [5] editor of Alpha2-Adrenergic Receptors (1988) and co-editor with Stephen Lanier of α2-Adrenergic ...
Louis Sanford Goodman (August 27, 1906 – November 19, 2000) was an American pharmacologist. He is best known for his collaborations with Alfred Gilman, Sr. , with whom he authored the popular textbook The Pharmacological Basis of Therapeutics in 1941 and pioneered the first chemotherapy trials using nitrogen mustard .
Gilman and Goodman are credited with the first use of intravenous chemotherapy treatment. [ 8 ] [ 9 ] After leaving his Army post in 1946, Gilman joined the faculty of Columbia's College of Physicians and Surgeons and moved to White Plains, New York , [ 1 ] then became the chairman of the new Department of Pharmacology at the Albert Einstein ...
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Alfred Goodman Gilman (July 1, 1941 – December 23, 2015) was an American pharmacologist and biochemist. [1] He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells."
The receptor occupancy model, which describes agonist and competitive antagonists, was built on the work of Langley, Hill, and Clark.The occupancy model was the first model put forward by Clark to explain the activity of drugs at receptors and quantified the relationship between drug concentration and observed effect.
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