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A lentigo (/ l ɛ n ˈ t aɪ ɡ oʊ /) (plural lentigines, / l ɛ n ˈ t ɪ dʒ ɪ n iː z /) is a small pigmented spot on the skin with a clearly defined edge, surrounded by normal-appearing skin. It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread.
Lentigo maligna is a histopathological variant of melanoma in situ. [6] Lentigo maligna is sometimes classified as a very early melanoma, [7] and sometimes as a precursor to melanoma. [8] When malignant melanocytes from a lentigo maligna have invaded below the epidermis, the condition is termed lentigo maligna melanoma. [2]
Histology slide of a solar lentigo. Differently from the melanotic nevi and the verrucous nevi on the skin, age spots change in color and in shape with time. Wang-Michelitsch and Michelitsch propose a hypothesis inspired by their misrepair-accumulation aging theory [12] for the development of age spots. [13]
Ink spot lentigo is a cutaneous condition characterized by skin lesions commonly occurring on the shoulders. [1] These lesions often cause alarm but are benign. They are an indication of excessive sun exposure so although ink spot lentigo is not premalignant, people with several of them maybe at increased risk of skin cancer due to UV damage.
Lentigo simplex is the most common form of lentigo. [ 2 ] : 29 A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood. Lentigo simplex is not induced by sun exposure, and it is not associated with any medical diseases or conditions.
Lentigo maligna melanoma is a melanoma that has evolved from a lentigo maligna, [1]: 695 as seen as a lentigo maligna with melanoma cells invading below the boundaries of the epidermis. [2] They are usually found on chronically sun damaged skin such as the face and the forearms of the elderly.
Lentiginosis refers to the presence of lentigines in large numbers or in a distinctive configuration. [1] These are spotted areas created by accumulation in the skin due to sun exposure.
The maximum shell length of this species is 100 mm, but more commonly it grows up to 75 mm. [2] As is the case in many strombids, the adult shell of Lentigo lentiginosus is very heavy and thick, with a characteristic deep stromboid notch, and a flared, very thick and posteriorly expanded outer lip.