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The Cambridge Pulmonary Hypertension Outcome Review has been a useful tool in clinical trials as it allows researchers to assess whether new medication or therapy is effective. The CAMPHOR has been utilized in clinical trials which investigate the effects of treprostinil, [12] [13] as well as trials which investigate sildenafil. [14] [15]
Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [7] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [7] [1] The condition may make it difficult to exercise. [7] Onset is typically gradual. [8]
Some tests which are commonly used include a CT scan of the chest, ventilation perfusion scan or a CT angiography (to rule out pulmonary hypertension due to chronic blood clots), pulmonary function test, and a cardiac MRI. Cardiac MRI is the preferred test to evaluate right ventricular structure and function in PAH.
Although higher pulmonary arterial pressures are associated with the development of HAPE, the presence of pulmonary hypertension may not in itself be sufficient to explain the development of edema; severe pulmonary hypertension can exist in the absence of clinical HAPE in subjects at high altitude. [9] [13]
Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by progressive blockage of the small veins in the lungs. [2] The blockage leads to high blood pressures in the arteries of the lungs, which, in turn, leads to heart failure .
Chest x-ray demonstrating severe atelectasis or collapse of the right lung and mediastinal shift towards the right. Atelectasis is the partial collapse of a lung that is reversible. There are numerous etiologies, including post-operative atelectasis, surfactant deficiency, mucus plugging, and foreign body aspiration.
pulmonary artery pressure (see pulmonary hypertension) [1] pulmonary alveolar proteinosis: Pap: Papanicolaou test (pap smear) PAPP-A: pregnancy-associated plasma protein A PAPVR: partial anomalous pulmonary venous return: PARA I: indicating a woman with one child (partus = birth) [1] PARA II: indicating a woman with two children (partus = birth ...
The main pulmonary trunk divides into the left and the right pulmonary artery. Pulmonary artery agenesis refers to the absence of one or both pulmonary arteries. Pulmonary artery agenesis refers to a rare congenital absence of pulmonary artery due to a malformation in the sixth aortic arch. It can occur bilaterally, with both left and right ...
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