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A therapeutic use exemption (TUE), also known as a temporary use exemption, is a term created in 1991 [1] and refers to an official medical document. The document gives an athlete permission to take a medication listed on the World Anti-Doping Agency’s (WADA) Prohibited List, normally prohibited because its use would be considered a performance enhancing drug.
However, free testosterone is difficult and expensive to measure (it requires a time-consuming dialysis step), and many laboratories do not offer this service. The free androgen index is intended to give a guide to the free testosterone level, but it is not very accurate (especially in males — see endocrine society commentary below).
But when considering calculated free testosterone, luteinizing hormones, and sex hormone-binding globulin levels, up to 20.2 percent of men would qualify as having subsets of the condition, like ...
The Quantiferon-TB Gold test (QFT-G) is a whole-blood test for use as an aid in diagnosing Mycobacterium tuberculosis infection, including latent tuberculosis infection (LTBI) and tuberculosis (TB) disease. [15] This test was approved by the U.S. Food and Drug Administration (FDA) in 2005. Blood samples are mixed with antigens (substances that ...
ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]
The test was first developed and described by the German physician Felix Mendel in 1908. [2] It is named after Charles Mantoux, a French physician who built on the work of Koch and Clemens von Pirquet to create his test in 1907. However, the test was unreliable due to impurities in tuberculin which tended to cause false results. [3]
In a clinical study conducted the sensitivity of the MTB/RIF test on just 1 sputum sample was 92.2% for culture-positive TB; 98.2% for smear+ and culture-positive cases; and 72.5% for smear-negative, culture-positive cases, with a specificity of 99.2%. Sensitivity and higher specificity were slightly higher when 3 samples were tested. [10]
The former test quantitates the amount of IFN-γ produced in response to the ESAT-6 and CFP-10 antigens from Mycobacterium tuberculosis, which are distinguishable from those present in BCG and most other non-tuberculous mycobacteria. The latter test determines the total number of individual effector T cells expressing IFN-γ. [citation needed]