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Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [ 14 ] and as an appetite stimulant . [ 15 ]
A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
In 2009, it was granted approval for the treatment of treatment-resistant depression. [ 4 ] Olanzapine/fluoxetine, or other antidepressant / antipsychotic combinations, are sometimes prescribed off-label for anxiety disorders , [ 5 ] eating disorders , [ 6 ] obsessive–compulsive disorder (OCD), [ 7 ] and posttraumatic stress disorder (PTSD).
Onset of Bipolar Disorder. Signs of bipolar disorder generally emerge in young adulthood. Research suggests that 70 percent of people with bipolar disorder experience their first manic episode ...
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication. Many patients will not develop these side effects, although ...
People with psychotic depression experience the symptoms of a major depressive episode, along with one or more psychotic symptoms, including delusions and/or hallucinations. [2] Delusions can be classified as mood congruent or incongruent, depending on whether or not the nature of the delusions is in keeping with the individual's mood state. [ 2 ]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
Symptoms must also cause clinically significant distress in important areas of everyday life (e.g. social or occupational). [22] For a diagnosis of a major depressive episode, the patient must also not have a history of manic or hypomanic episodes and their symptoms cannot meet the criteria for a mixed episode. [23]
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