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Dermatology Acantholysis is the loss of intercellular connections , such as desmosomes , resulting in loss of cohesion between keratinocytes , [ 1 ] seen in diseases such as pemphigus vulgaris . [ 2 ]
In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test. [1] Tzanck cells (acantholytic cells) are found in: Herpes simplex [2] Varicella and herpes zoster
Dermatology Grover's disease ( GD ) is a polymorphic, pruritic , papulovesicular dermatosis characterized histologically by acantholysis [ 2 ] : 529 with or without dyskeratosis. [ 3 ] Once confirmed, most cases of Grover's disease last six to twelve months, which is why it was originally called "transient".
Skin fragility–wooly hair syndrome Lethal acantholytic epidermolysis bullosa ARVD Paraneoplastic pemphigus Stevens–Johnson syndrome: Plakoglobin: Naxos disease Striate palmoplantar keratoderma ARVD Plakophilin 1: Ectodermal dysplasia–skin fragility syndrome: Plakophilin 2: ARVD Corneodesmosin: Hypertrichosis simplex of the scalp
Suture granuloma, with multinucleated giant cells surrounding (grey) suture material. Foreign bodies indicate a foreign body granuloma. Specific forms of multinucleated giant cells include the Touton giant cell, which contains a ring of nuclei surrounding a central homogeneous cytoplasm, with foamy cytoplasm surrounding the nuclei.
Micrograph of keratinocytes, basal cells and melanocytes in the epidermis Keratinocytes (stained green) in the skin of a mouse. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1]
With a win over the Steelers, the Chiefs ensured the AFC playoffs will run through Arrowhead Stadium, as Kansas City clinched home-field advantage.
Pemphigus foliaceus is an autoimmune blistering disease of the skin. [1] Pemphigus foliaceus causes a characteristic inflammatory attack at the subcorneal layer of epidermis, which results in skin lesions that are scaly or crusted erosions with an erythematous (red) base. [2] Mucosal involvement is absent even with widespread disease. [3]