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The SI unit for permeability is the square metre (m 2). A practical unit for permeability is the darcy (d), or more commonly the millidarcy (md) (1 d ≈ 10 −12 m 2). The name honors the French Engineer Henry Darcy who first described the flow of water through sand filters for potable water supply. Permeability values for most materials ...
The diffusion coefficient can be combined with the reaction equilibrium constant to get the final form of the equation, where is the permeability of the membrane. The relationship being P = K D {\displaystyle P=KD}
In SI units, permeability is measured in henries per meter (H/m), or equivalently in newtons per ampere squared (N/A 2). The permeability constant μ 0, also known as the magnetic constant or the permeability of free space, is the proportionality between magnetic induction and magnetizing force when forming a magnetic field in a classical vacuum.
The darcy is referenced to a mixture of unit systems. A medium with a permeability of 1 darcy permits a flow of 1 cm 3 /s of a fluid with viscosity 1 cP (1 mPa·s) under a pressure gradient of 1 atm/cm acting across an area of 1 cm 2. Typical values of permeability range as high as 100,000 darcys for gravel, to less than 0.01 microdarcy for ...
Equation 1: = / / The drug apparent permeability (P app) is calculated by normalizing the drug flux (j) over the initial concentration of the API in the donor compartment (c 0) as: Equation 2: = / Dimensionally, the P app represents a velocity, and it is normally expressed in cm/sec. The highest is the permeability, the highest is expected to ...
In electromagnetism, permeance is the inverse of reluctance.In a magnetic circuit, permeance is a measure of the quantity of magnetic flux for a number of current-turns. A magnetic circuit almost acts as though the flux is conducted, therefore permeance is larger for large cross-sections of a material and smaller for smaller cross section lengths.
Likewise, it is used to calculate lipophilic efficiency in evaluating the quality of research compounds, where the efficiency for a compound is defined as its potency, via measured values of pIC 50 or pEC 50, minus its value of log P. [27] Drug permeability in brain capillaries (y axis) as a function of partition coefficient (x axis) [28]
The method uses scattering parameters of a material sample embedded in a waveguide, namely and , to calculate permittivity and permeability data. and correspond to the cumulative reflection and transmission coefficient of the sample that are referenced to the each sample end, respectively: these parameters account for the multiple internal reflections inside the sample, which is considered to ...