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In some interactions between lysogenic phages and bacteria, the lysogenic conversion may occur, which can also be called phage conversion. It is when a temperate phage induces a change in the phenotype of the infected bacteria that is not part of a usual phage cycle. Changes can often involve the external membrane of the cell by making it ...
Lysogenic conversion is a process that occurs between a bacterium and a phage that is often beneficial for the bacteria. In lysogenic conversion, the phage inserts specific characteristics into the bacterial genes causing the bacteria to have better survival.
If so, CI represses the early promoters and the infection is shunted into the lysogenic pathway. N is an anti-termination factor that is needed for the transcription of the delayed early genes. Delayed early genes: These include the replication genes O and P and also Q , which encodes the anti-terminator responsible for transcription of all the ...
Transduction This is an illustration of the difference between generalized transduction, which is the process of transferring any bacterial gene to a second bacterium through a bacteriophage and specialized transduction, which is the process of moving restricted bacterial genes to a recipient bacterium. While generalized transduction can occur ...
Lambda phage is a non-contractile tailed phage, meaning during an infection event it cannot 'force' its DNA through a bacterial cell membrane. It must instead use an existing pathway to invade the host cell, having evolved the tip of its tail to interact with a specific pore to allow entry of its DNA to the hosts.
At this point they initiate the reproductive cycle, resulting in lysis of the host cell. As the lysogenic cycle allows the host cell to continue to survive and reproduce, the virus is replicated in all offspring of the cell. An example of a bacteriophage known to follow the lysogenic cycle and the lytic cycle is the phage lambda of E. coli. [53]
Infection begins when the gp9 tailspike of the P22 phage binds to the O-antigen lipopolysaccharide on the surface of Salmonella typhimurium host. [1] The virion's tail fiber protein has endorhamnosidase activity, which cleaves the O-antigen chain. [3] Upon infection, P22 can enter either a lytic or lysogenic growth pathway. [1]
Another important area of interest is the control of prophage gene expression with many of the lysogenic conversion genes (gene conversion) being tightly regulated. [15] This process is capable of converting non-pathogenic bacteria into pathogenic bacteria that can now produce harmful toxins [15] such as in staph infections. Since the specific ...