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Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum ...
1.3 million (2015) [ 5 ] Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue (fibrosis) and regenerative nodules as a result of chronic liver disease. [ 6 ][ 7 ][ 8 ] Damage to the liver leads ...
Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. [1] ". Chronic liver disease" refers to disease of the liver which lasts over a period of six months. It consists of a wide range of liver ...
Emergency medicine. A liver injury, also known as liver laceration, is some form of trauma sustained to the liver. This can occur through either a blunt force such as a car accident, or a penetrating foreign object such as a knife. [ 1 ] Liver injuries constitute 5% of all traumas, making it the most common abdominal injury. [ 2 ]
2. You May Experience Pain or Discomfort In Your Upper Right Abdomen. Pain or discomfort in the upper right side of your abdomen could signal NAFLD. This is where the liver is located, and if it ...
Hepatitis, inflammation of the liver, is caused by various viruses (viral hepatitis) also by some liver toxins (e.g. alcoholic hepatitis), autoimmunity (autoimmune hepatitis) or hereditary conditions. [6] Alcoholic liver disease is a hepatic manifestation of alcohol overconsumption, including fatty liver disease, alcoholic hepatitis, and ...
hepatic coma. [ 3 ] Hepatic encephalopathy (HE) is an altered level of consciousness as a result of liver failure. [ 2 ] Its onset may be gradual or sudden. [ 2 ] Other symptoms may include movement problems, changes in mood, or changes in personality. [ 2 ] In the advanced stages it can result in a coma.