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The pancreas is located in the visceral region, and is a major part of the digestive system required for proper digestion and subsequent assimilation of macronutrient substances required for living. Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. Bicarbonate is useful in neutralizing the acidic gastric ...
The primary function of pancreas ductal cells is to secrete a bicarbonate-rich, isotonic fluid. This fluid washes away the inactive form of digestive enzymes in the ductal system, neutralizes stomach acidity and mucins, and creates a pH environment necessary for the pancreas's normal function. [4]
The exocrine pancreas is one of two compartments that include digestive-acting acinar cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. [1] These cells are commonly known as duct cells, and secrete an aqueous bicarbonate solution under stimulation by the hormone secretin. They also secrete ...
The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. [2] 99% of the pancreas is exocrine and 1% is endocrine.
Pancreas is both an endocrine and an exocrine gland, in that it functions to produce endocrinic hormones released into the circulatory system (such as insulin, and glucagon), to control glucose metabolism, and also to secrete digestive / exocrinic pancreatic juice, which is secreted eventually via the pancreatic duct into the duodenum ...
The pancreas produces and releases important digestive enzymes in the pancreatic juice that it delivers to the duodenum. [24] The pancreas lies below and at the back of the stomach. It connects to the duodenum via the pancreatic duct which it joins near to the bile duct's connection where both the bile and pancreatic juice can act on the chyme ...
Secretin is used in diagnostic tests for pancreatic function; secretin is injected and the pancreatic output can then be imaged with magnetic resonance imaging, a noninvasive procedure, or secretions generated as a result can gathered either through an endoscope or through tubes inserted through the mouth, down into the duodenum. [36] [37] [38]
The bicarbonate ion (hydrogencarbonate ion) is an anion with the empirical formula HCO − 3 and a molecular mass of 61.01 daltons; it consists of one central carbon atom surrounded by three oxygen atoms in a trigonal planar arrangement, with a hydrogen atom attached to one of the oxygens.