Search results
Results from the WOW.Com Content Network
Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH) 2 where Ph is the phenyl group C 6 H 5 - and B(OH) 2 is a boronic acid containing a phenyl substituent and two hydroxyl groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis.
The general structure of a boronic acid, where R is a substituent. A boronic acid is an organic compound related to boric acid (B(OH) 3) in which one of the three hydroxyl groups (−OH) is replaced by an alkyl or aryl group (represented by R in the general formula R−B(OH) 2). [1]
The mechanism of organotrifluoroborate-based Suzuki-Miyaura coupling reactions has recently been investigated in detail. The organotrifluoroborate hydrolyses to the corresponding boronic acid in situ, so a boronic acid can be used in place of an organotrifluoroborate, as long as it is added slowly and carefully. [7] [8]
Removal of the BOC group in amino acids can be accomplished with strong acids such as trifluoroacetic acid in dichloromethane, or with HCl in methanol. [2] [3] [4] A complication may be the tendency of the t-butyl cation intermediate to alkylate other nucleophiles; scavengers such as anisole or thioanisole may be used.
n-Butyl glycidyl ether is metabolized renally to butoxyacetic acid, 3-butoxy-2-hydroxypropionic acid and 3-butoxy-2-acetylaminopropionic acid. [5] [6] Safety
4-Formylphenyl boronic acid crystallizes in colorless needles [2] or is obtained as an odorless, whitish powder, which dissolves little in cold but better in hot water. The compound is quite stable [4] and readily forms dimers and cyclic trimeric anhydrides, which complicate purification and tend to protodeboronize, a secondary reaction that occurs frequently in the Suzuki coupling, with ...
Butoxyacetic acid is an aliphatic organic chemical. It is a liquid. [2] It has the formula C 6 H 12 O 3 and CAS Registry Number of 2516-93-0. [3] It is REACH registered with the EC number 677-344-8. [4] n-Butyl glycidyl ether is metabolized renally to this compound as is 2-butoxyethanol.
W 2 (O-t-Bu) 6 (C 3 H 4) + 2H 2 C=C=CH 2 → W 2 (O-t-Bu) 6 (C 3 H 4) 2 Hexa(tert-butoxy)ditungsten(III) reacting with allene. The product of 1:1 adduction can further react with carbon monoxide to form a similar structure to 1:2 adduction but adducted with carbon monoxide instead of allene: