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The miR-15 microRNA precursor family is made up of small non-coding RNA genes that regulate gene expression. The family includes the related mir-15a and mir-15b sequences, as well as miR-16-1, miR-16-2, miR-195 and miR-497. These six highly conserved miRNAs are clustered on three separate chromosomes. [1]
In molecular biology, mir-46 and mir-47 are microRNA expressed in C. elegans from related hairpin precursor sequences. [1] The predicted hairpin precursor sequences for Drosophila mir-281 (MI0000366, MI0000370) [2] [3] are also related and, hence, belong to this family. The hairpin precursors (represented here) are predicted based on base ...
Consensus structure of the mir-2 family hairpin precursor. Mir-2 hairpin precursor sequences are highly conserved, in particular in their 3' arm in which the first 10 nucleotides are identical to all family members. Functional mir-2 microRNAs come from the 3' arm of the precursors, and most of them have the same Drosha processing point.
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miR-146 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer . [ 1 ] This sequence then associates with RISC which effects RNA interference .
The miR-16 microRNA precursor family is a group of related small non-coding RNA genes that regulates gene expression. miR-16, miR-15, mir-195 and miR-497 are related microRNA precursor sequences from the mir-15 gene family ().
miR-138 is a family of microRNA precursors found in animals, including humans. [1] MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. [2] The excised region or, mature product, of the miR-138 precursor is the microRNA mir-138.
406947 n/a Ensembl ENSG00000283904 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 21: 25.57 – 25.57 Mb n/a PubMed search n/a Wikidata View/Edit Human MiR-155 is a microRNA that in humans is encoded by the MIR155 host gene or MIR155HG. MiR-155 plays a role in various physiological and pathological processes. [7] [8] [9] Exogenous molecular control in ...