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tert-Butyloxycarbonyl protecting group. The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group [1] (BOC group) is an acid-labile protecting group used in organic synthesis. The BOC group can be added to amines under aqueous conditions using di-tert-butyl dicarbonate in the presence of a base such as sodium hydroxide:
1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture of fentanyl, as well as various related derivatives such as butyrylfentanyl, furanylfentanyl, benzylfentanyl and homofentanyl, among others.
N-t-BOC-MDMA is a chemical compound which can be both a synthetic precursor to, or a prodrug of the empathogenic drug MDMA. It was first identified in Australia in 2015 as a seizure by customs, and has subsequently been found in China, the Netherlands and other European countries.
Budipine can be prepared from the 1-tert-butyl-4-piperidone [1465-76-5] directly by treatment with benzene in the presence triflic acid. [12] This method of synthesis enables a 99% yield of product. Thieme Synthesis: [ 13 ]
Substituted and dehydro derivatives of 4-piperidinone are intermediates in alkaloid syntheses. [1] The N-protonated derivative is typically isolated as the hydrate (HO) 2 C(CH 2) 4 NH + 2. [2] It is a List I chemical in the United States as it is a precursor to fentanyl. Fentanyl synthesis using the Gupta method starting from 4-piperidone
The Associated Press 2024 NFL All-Pro team selected by a national panel of 50 media members: First team Offense. Quarterback — Lamar Jackson, Baltimore. Running Back — Saquon Barkley, Philadelphia
Over a 45-years span — between 1975 and 2020 — improvements in cancer screenings and prevention strategies have reduced deaths from five common cancers more than any advances in treatments ...
Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. [1] Since this compound can be regarded formally as the acid anhydride derived from a tert-butoxycarbonyl (Boc) group, it is commonly referred to as Boc anhydride. This pyrocarbonate reacts with amines to give N-tert-butoxycarbonyl or so-called Boc
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