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In vitro studies have found gadolinium-based contrast agents to be neurotoxic, [33] and a study found signal intensity in the dentate nucleus of MRI (indicative of gadolinium deposition) to be correlated with lower verbal fluency. [34] Confusion is often reported as a possible clinical symptom. [33]
It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4] [5] The paramagnetic property of gadoteric acid reduces the T1 relaxation time (and to some extent the T2 and T2* relaxation times) in MRI, which is the source of its clinical utility. Because ...
Nanoparticles of gadolinium oxide is a potential contrast agent for magnetic resonance imaging (MRI). A dextran-coated preparation of 20–40 nm sized gadolinium oxide particles had a relaxivity of 4.8 s −1 mM −1 per gadolinium ion at 7.05 T (an unusually high field compared to the clinically used MRI scanners which mostly range from 0.5 to ...
Gadolinium is used in magnetic resonance imaging as an MRI contrast agent or gadolinium-based contrast agent (GBCA). [3] In the 3+ oxidation state, the metal has seven unpaired electrons. This causes water around the contrast agent to relax quickly, enhancing the quality of the MRI scan.
Cardiac MRI does not pose any specific risks compared to other indications for imaging. [11] Gadolinium based contrast medium is frequently used in CMR and has been associated with nephrogenic systemic fibrosis, predominantly using linear compounds in patients with renal disease.
Gadopiclenol, sold under the brand name Elucirem among others, is a contrast agent used with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and in the body. [2] [7] Gadopiclenol is a paramagnetic macrocyclic non-ionic complex of gadolinium. [2]
Gadodiamide is a contrast medium used for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. It provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS).
Gadolinium is a silvery-white metal when oxidation is removed. It is a malleable and ductile rare-earth element. Gadolinium reacts with atmospheric oxygen or moisture slowly to form a black coating. Gadolinium below its Curie point of 20 °C (68 °F) is ferromagnetic, with an attraction to a magnetic field higher than that of nickel.