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Some side effects may be ameliorated by using a shorter dosing interval (weekly or every ten days instead of twice monthly with testosterone enanthate or testosterone cypionate). 100 mg weekly gives a much lower peak level of testosterone than does 200 mg every two weeks, while still maintaining the same total dose of androgen.
The bioavailability of anastrozole in humans is unknown, but it was found to be well-absorbed in animals. [2] [6] Absorption of anastrozole is linear over a dosage range of 1 to 20 mg/day in humans and does not change with repeated administration. [3] [4] [6] Food does not significantly influence the extent of absorption of anastrozole.
Anastrozole distributes completely around the body and only 40% of the drug is bound to plasma proteins. The elimination of anastrozole is slow and the elimination half-life is 40–50 hours. Most of the drug dose is excreted in the urine but some part is excreted in feces.
Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
Estradiol valerate is usually used in the treatment of advanced prostate cancer in men at a dosage of 30 mg or more every 1 to 2 weeks by intramuscular injection. [13] In transgender women, estradiol valerate given by intramuscular injection is usually used at a dosage of 5 to 20 mg, but up to 30 to 40 mg, once every 2 weeks.
Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.
once daily in the morning q.d.p.m. quaque die post meridiem: once daily in the evening q.d.s. quater die sumendus: 4 times a day can be mistaken for "qd" (every day) q.p.m. quaque die post meridiem: every evening (every day after noon) q.h. quaque hora: every hour q.h.s. quaque hora somni: every night at bedtime
Estradiol patches have an extended duration and are available for twice-weekly (3–4-day) and once-weekly (7-day) application, while gels, emulsions, and sprays are administered daily. [ 186 ] [ 15 ] [ 10 ] [ 210 ] There are two types of estradiol patches: reservoir patches , which have been described as first-generation patches, and matrix ...
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