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The bulboid corpuscles (end-bulbs of Krause, Krause corpuscles) are cutaneous receptors in humans and other animals. The end-bulbs of Krause were named after the German anatomist Wilhelm Krause (1833–1910). [1] [2]
Krause discovered and described mechanoreceptors that were to become known as "Krause's corpuscles", sometimes referred to as "Krause's end-bulbs". [citation needed] His name is also associated with: "Krause's membranes": defined as isotropic bands in striated muscle fiber that consist of disks of sarcoplasm and connect the individual fibrils ...
Bachmann's bundle – Jean George Bachmann (1877–1959), German-American physiologist; Balbiani bodies – Édouard-Gérard Balbiani; Bartholin's gland – Caspar Bartholin the Younger (1655–1738), Danish anatomist
The end-bulb of Krause or bulboid corpuscle detects temperatures above body temperature. Ruffini's end organ detects temperatures below body temperature. TRPV1 is a heat-activated channel that acts as a small heat detecting thermometer in the membrane which begins the polarization of the neural fiber when exposed to changes in temperature.
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This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement. [3] They are at the highest density around the fingernails where they act in monitoring slippage of objects along the surface of the skin, allowing modulation of grip on an object.