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Priming is the first contact that antigen-specific T helper cell precursors have with an antigen. It is essential to the T helper cells' subsequent interaction with B cells to produce antibodies. [1] Priming of antigen-specific naive lymphocytes occurs when antigen is presented to them in immunogenic form (capable of inducing an immune response).
T-cell dependent B-cell activation, showing TH2-cell (left) B-cell (right) and several interaction molecules self-made according to Janeway et al, Immunologie (Berlin, 2002) Following development in the thymus, these cells (termed recent thymic emigrants (RTE)) egress from the thymus and home to secondary lymphoid organs (SLO; spleen and lymph ...
Cell–cell interaction refers to the direct interactions between cell surfaces that play a crucial role in the development and function of multicellular organisms. These interactions allow cells to communicate with each other in response to changes in their microenvironment. This ability to send and receive signals is essential for the ...
Immunological synapse between Jurkat T cell expressing GFP-actin (green) and Raji B cell stained with CMAC (blue). Synapse formation was induced by Staphylococcal enterotoxin E superantigen . In immunology , an immunological synapse (or immune synapse ) is the interface between an antigen-presenting cell or target cell and a lymphocyte such as ...
B7 is a type of integral membrane protein found on activated antigen-presenting cells (APC) that, when paired with either a CD28 or CD152 surface protein on a T cell, can produce a costimulatory signal or a coinhibitory signal to enhance or decrease the activity of a MHC-TCR signal between the APC and the T cell, respectively.
Plasma cell: Lymphocyte: B cell: Plasma B cells; Effector B cells; Plasmocytus; 8-10 Active B cells that produces large amounts of antibodies [4] [15] Memory B cell: Lymphocyte: B cell: MBC; 8-10 Memorizes the characteristics of the antigens; Triggers an accelerated and robust secondary immune response [4] [16] Killer T cell: Lymphocyte: T cell ...
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
T lymphocytes regulate the growth and differentiation of T cells and certain B cells through the release of secreted protein factors. [12] These factors, which include interleukin 2 (IL2), are secreted by lectin- or antigen-stimulated T cells, and have various physiological effects. IL2 is a lymphokine that induces the proliferation of ...
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