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[1] [2] [3] Cohn describes its use to detect the principal components of digitalis (note that they may not be alkaloids). [4] The reaction with this reagent is also known as the Keller–Kiliani reaction, after C. C. Keller and H. Kiliani, who both used it to study digitalis in the late 19th century.
Keller's reagent can refer to two different reagents: Keller's reagent (metallurgy), used to etch aluminum alloys; Keller's reagent (organic), used to detect alkaloids
The Kiliani–Fischer synthesis, named for German chemists Heinrich Kiliani and Emil Fischer, is a method for synthesizing monosaccharides.It proceeds via synthesis and hydrolysis of a cyanohydrin, followed by reduction of the intermediate acid to the aldehyde, thus elongating the carbon chain of an aldose by one carbon atom while preserving stereochemistry on all the previously present chiral ...
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. [1] Their beneficial medical uses include treatments for congestive heart failure and cardiac arrhythmias ; however, their relative toxicity prevents them ...
[1] Three methods are used for detecting oleandrin in the blood. Fluorescence polarization immunoassay is widely used. This test is slower and has a lower sensitivity than digoxin immunoassay (Digoxin III). [11] A direct analytic technique like liquid chromatography-electrospray tandem mass spectrometry is used when there are medical or legal ...
The study, which was published in Nature Medicine on January 20, analyzed data from more than 2 million people with diabetes who took GLP-1 receptor agonist medications like Ozempic and Wegovy.
The term derives from card-"heart" (from Greek καρδία kardiā) and the suffix -enolide, referring to the lactone ring at C17. [2] Cardenolides are a class of steroids (or aglycones if viewed as cardiac glycoside constituents), and cardenolides are a subtype of this class (see MeSH D codes list ).
A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and gastrointestinal problems, among others.