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US 52 crosses the North Carolina state line, after traveling 159.7 miles (257.0 km) through South Carolina, continuing on towards Wadesboro. [ 7 ] US 52 is a major highway between Charleston and Florence, all of which is four-lane or more with some sections signed 60-mile-per-hour (97 km/h).
South Carolina Highway 642 (SC 642, also known as Dorchester Road), is a 19.292-mile (31.047 km) state highway in the southeastern part of the U.S. state of South Carolina. It travels within the Summerville and North Charleston areas.
Interstate 526 (I-526) is a 19.56-mile (31.48 km) auxiliary route of I-26, providing a partial beltway around Charleston, South Carolina, in the United States.The route serves several purposes, firstly, as a bypass for through traffic on U.S. Route 17 (US 17) to avoid downtown Charleston, and, secondly, for traffic on I-26 bound for the coastal towns located north and south of Charleston.
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The South Carolina Department of Transportation (SCDOT) operates and maintains one welcome center and seven rest areas along I-26. Welcome centers, which have a travel information facility on site, are located at milemarker 3 (eastbound); rest areas are located at milemarkers 63 (east and westbound), 123 (east and westbound), 150 (eastbound), 152 (westbound), and 204 (eastbound). [2]
US 78 enters South Carolina by crossing the Savannah River in North Augusta; sharing concurrences with US 1, US 25, US 278 and South Carolina Highway 121 (SC 121). In the immediate 2-mile (3.2 km) area, it sheds most concurrencies, sharing only with US 1 towards Aiken; it also connects with Interstate 520 (I-520), which is a partial beltway around the Augusta metropolitan area.
South Carolina Highway 61 (SC 61) is a 67-mile-long (108 km) state highway in the U.S. state of South Carolina. The highway is designated on a north–south direction, but physically travels in an east–west direction, from SC 30 in Charleston to U.S. Route 78 (US 78) near Branchville .
US 301 at the SC 260 intersection in Manning.. US 301 was established in 1932 as a replacement of the piece of US 17-1 north of Wilson and the whole of US 217. Thus US 301 initially ran from US 17 (now US 76) at Pee Dee northeast through Dillon, South Carolina, into North Carolina, and Virginia, ending at U.S. Route 1 in Petersburg, Virginia.
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