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Gleason score 3+4=7 (prognostic grade group II) indicating the majority is pattern 3; Gleason score 4+3=7 (prognostic grade group III) where pattern 4 is dominant; [6] Gleason score 4+4=8 (prognostic grade group IV); Gleason scores 9-10 (prognostic grade group V). [7] Prostate cancers with a Gleason score ≤ 6 usually have rather good prognoses.
Diverticulitis, also called colonic diverticulitis, is a gastrointestinal disease characterized by inflammation of abnormal pouches—diverticula—that can develop in the wall of the large intestine. [1] Symptoms typically include lower abdominal pain of sudden onset, but the onset may also occur over a few days. [1]
Diverticulitis is defined as diverticular disease with signs and symptoms of diverticular inflammation. Clinical features of acute diverticulitis include constant abdominal pain, localized abdominal tenderness in the left lower quadrant of the abdomen, nausea, vomiting, constipation or diarrhea, fever and leukocytosis .
Complicated acute diverticulitis is distinguished from uncomplicated diverticulitis by the presence of abscess or colonic perforation. Chronic smoldering diverticulitis is caused by recurrent acute diverticulitis that does not respond to medical treatment but does not progress to complications such as abscess, peritonitis, enteric fistula, or ...
This lack of a single standard led to confusion in patients' treatment and difficulties in evaluation of potential new treatments. [1] Gleason's technique, which he published in the journal Cancer Chemotherapy Reports in 1966, focused on two details of the architecture of the cancer cells, and assigned a score of one to five to each attribute ...
While a low-fiber diet is generally used for acute diverticulitis, the NIH guidelines recommend a high-fiber diet for patients with diverticulosis (a condition that may lead to diverticulitis). [17] A Mayo Clinic review from 2011 showed that a high-fiber diet can prevent diverticular disease.
A Meckel's diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine present at birth and a vestigial remnant of the vitelline duct.It is the most common malformation of the gastrointestinal tract and is present in approximately 2% of the population, [1] with males more frequently experiencing symptoms.
In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient.
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