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Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. Though temsirolimus shows activity on its own, it is also known to be converted to sirolimus (rapamycin) in vivo; [4] therefore, its activity may be more attributed to its metabolite rather than the prodrug itself (despite claims to the ...
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The Sierra Madre Oriental range to the west separates the Tamaulipan mezquital from the drier Chihuahuan Desert.The Tamaulipan matorral is a transitional ecoregion between the mezquital and the Sierra Madre Oriental pine-oak forests to the west and the Veracruz moist forests to the south.
The geography of Texas is diverse and large. Occupying about 7% of the total water and land area of the U.S., [1] it is the second largest state after Alaska, and is the southernmost part of the Great Plains, which end in the south against the folded Sierra Madre Oriental of Mexico.
Texas trees that change foliage color in the fall tend to do so later in the season, according to Texas Parks & Wildlife. Local booking site SmokyMountains.com predicts when fall foliage will ...
Gould's Ecoregions of Texas (1960). [1] These regions approximately correspond to the EPA's level 3 ecoregions. [2]The following is a list of widely known trees and shrubs found in Texas.
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Texas has been the leading state in petroleum production since discovery of the Spindletop oil field in 1901. [11] As of October 2017, the State of Texas (if treated as its own nation) is the 7th largest oil producing nation in the world, with production totaling approximately 3.78 million barrels (600 thousand cubic meters ) per day of oil ...