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Clinical findings include back pain, paraparesis, kyphosis, sensory disturbances, and bowel and bladder dysfunction. [5] Signs of associated extraskeletal tuberculosis include cough, expectoration, swollen lymp nodes, diarrhea, and abdominal swelling. [5] The earliest and most common symptom is back pain, which worsens with activity.
Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known as latent tuberculosis . [ 1 ] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [ 1 ]
Tuberculous pericarditis is a condition that accounts for 1-2% of presentations of tuberculosis outside of the lungs. [2] It is found in people of all ages and typically affects males more frequently than females. [4] Tuberculosis is also one of the leading causes of effusive pericarditis worldwide. [6]
Tuberculous dactylitis affects the short tubular bones of the hands and feet in children. It often follows a mild course without fever and acute inflammatory signs as opposed to acute osteomyelitis. There may be a gap of a few months to 2 to 3 years from the time of initial infection to the point of diagnosis. [5] [6] [7]
Symptoms of M. tuberculosis include coughing that lasts for more than three weeks, hemoptysis, chest pain when breathing or coughing, weight loss, fatigue, fever, night sweats, chills, and loss of appetite. M. tuberculosis also has the potential of spreading to other parts of the body. This can cause blood in urine if the kidneys are affected ...
Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. [1] [6] Historically, transmission of Mycobacterium bovis from dairy consumption was another frequent cause of tuberculous lymphadenitis, but incidence has drastically decreased in developed countries since the advent of pasteurization and other efforts to prevent bovine ...
The two most common commercially available tests are the amplified mycobacterium tuberculosis direct test (MTD, Gen-Probe) and Amplicor. [15] In 2007, review concluded that for diagnosing tuberculous meningitis "Individually, the AMTD test appears to perform the best (sensitivity 74% and specificity 98%)", they found the pooled prevalence of TB ...
Miliary tuberculosis is a form of tuberculosis that is characterized by a wide dissemination into the human body and by the tiny size of the lesions (1–5 mm). Its name comes from a distinctive pattern seen on a chest radiograph of many tiny spots distributed throughout the lung fields with the appearance similar to millet seeds—thus the term "miliary" tuberculosis.