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The disease affects both children and adults and is characterized by systemic thrombotic microangiopathy (TMA), the formation of blood clots in small blood vessels throughout the body, which can lead to stroke, heart attack, kidney failure, and death.
Protein C is vitamin K-dependent. Patients with Protein C deficiency are at an increased risk of developing skin necrosis while on warfarin. Protein C has a short half life (8 hour) compared with other vitamin K-dependent factors and therefore is rapidly depleted with warfarin initiation, resulting in a transient hypercoagulable state.
The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.
Heart disease: Problems with your heart and arteries can increase your risk of plaque buildup or blood clots that can cause a stroke. Diabetes: High blood sugar can cause damage to blood vessels ...
Sickle cell disease is a group of inherited blood disorders, caused by a genetic abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [57] Under certain circumstances, this leads to the red blood cells adopting an abnormal sickle -like shape; with this shape, they are unable to deform as they pass through capillaries ...
Atherosclerosis. Atherosclerosis contributes to about half of all deaths in Western countries, including the United States. Globally, it causes about 10 million deaths per year.. Atherosclerosis ...
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). [ 1 ] [ 2 ] Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not ...
Blood clots in veins don't typically cause strokes, but they can lead to deep vein thrombosis, aka the reason you should stretch your legs during a long flight. Clots that form in the deep veins ...
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262 Neil Avenue # 430, Columbus, Ohio · Directions · (614) 221-7464