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The mitotic index is therefore an important prognostic factor predicting both overall survival and response to chemotherapy in most types of cancer. It may lose much of its predictive value for elderly populations. For example, a low mitotic index loses any prognostic value for women over 70 years old with breast cancer. [3]
The area provides a reference unit, for example in reference ranges for urine tests. [3]Used for grading of soft tissue tumors: Grading, usually on a scale of I to III, is based on the degree of differentiation, the average number of mitoses per high-power field, cellularity, pleomorphism, and an estimate of the extent of necrosis (presumably a reflection of rate of growth).
Testosterone levels in males and females ; Total testosterone Stage Age range Male Female Values SI units Values SI units ; Infant: Premature (26–28 weeks) 59–125 ng/dL: 2.047–4.337 nmol/L
Usually the number of mitotic figures is expressed as the total number in a defined number of high power fields, such as 10 mitoses in 10 high power fields. Since the field of vision area can vary considerably between different microscopes, the exact area of the high power fields should be defined in order to compare results from different studies.
In histopathology, the mitosis rate (mitotic count or mitotic index) is an important parameter in various types of tissue samples, for diagnosis as well as to further specify the aggressiveness of tumors. For example, there is routinely a quantification of mitotic count in breast cancer classification. [74]
Lymph Node – The lymph node values (NX, N0, N1, N2 or N3) depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.) [25] [26] The armpit is designated as ...
Women between the ages of 63 and 99 only needed an average of 3,600 steps per day to reduce their heart failure risk by 26%. Getty Images During a period of 7½ years, there were 407 cases of ...
Undifferentiated uterine sarcoma, or undifferentiated (high-grade) endometrial stromal sarcoma, does not resemble normal endometrial stroma and behaves much more aggressively, frequently metastasizing. The differential includes leukemia, lymphoma, high-grade carcinoma, carcinosarcoma, and differentiated pure sarcomas.