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A xanthoma (pl. xanthomas or xanthomata) (condition: xanthomatosis) is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states. [2] They are cutaneous manifestations of lipidosis in which lipids accumulate in large foam cells within the skin. [ 2 ]
Xanthoma variants associated with hyperlipoproteinemia subtypes Xanthoma variant Associated subtype(s) Xanthoma striatum palmare: III Plane xanthoma: II Plane xanthoma specifically of the antecubital fossa and web spaces of the fingers: IIb Eruptive xanthoma: I, IV, V Tendinous xanthoma: II Xanthelasma: II, III Tuberous xanthoma: II, III
Tuberoeruptive xanthoma (tuberous xanthoma) Tumoral calcinosis; Variegate porphyria (mixed hepatic porphyria, mixed porphyria, South African genetic porphyria, South African porphyria) Verruciform xanthoma; Waxy skin; Wilson's disease (hepatolenticular degeneration) Xanthelasma palpebrarum (xanthelasma) Xanthoma diabeticorum; Xanthoma planum ...
Verruciform xanthoma is an uncommon benign [1] lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile. [ 2 ] : 535 The verruciform was first described by Shafer in 1971 on the oral mucosa. [ 3 ]
Touton giant cells are also referred to as xanthelasmatic cells due to the fact they are found in lesions associated with xanthomas which are skin growths with yellow, lipid filled deposits. Touton giant cells are often frequently observed in granulomatous inflammation, which is a type of inflammation caused by the clustering of immune cells ...
Papular xanthoma is a cutaneous condition that is a rare form of non-X histiocytosis. [1]: 718 ...
Atypical fibroxanthoma (AFX) of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically. [2]: 613 Atypical fibroxanthoma manifests as a hard, pink or red papule or nodule that grows over the course of several months and may bleed or ulcerate.
Xanthoma disseminatum is a rare cutaneous condition that preferentially affects males in childhood, characterized by the insidious onset of small, yellow-red to brown papules and nodules that are discrete and disseminated. [2]: 717 It is a histiocytosis syndrome. [3]