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Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or ...
Optic nerve gliomas have low mortality but extremely high prevalence of vision loss and eye-bulging exophthalmos) in children. [4] As of 2014, approximately 1000 cases had been reported. [ 4 ]
This produces a dark red staining of the muscle fibers given the name "ragged red fibers". While ragged red fibers are seen in normal aging, amounts in excess of normal aging give a diagnosis of a mitochondrial myopathy. [citation needed] Polymerase chain reaction (PCR) from a sample of blood or muscle tissue can determine a mutation of the mtDNA.
In children and teenagers mean exophthalmometric measurements increase with age: Less than 4 years old (13.2 mm), 5–8 years old (14.4 mm), 9–12 years old (15.2 mm) and 13–17 years old (16.2 mm). [4] Axial Length of the eye affects exophthalmometer reading. Pseudoproptosis may be seen in severe myopia. [5]
Hyperthyroidism has unique effects in children on growth and pubertal development, e.g. causing epiphyseal maturation. In growing children, accelerated bone growth from hyperthyroidism can increase osteogenesis in the short term, but generally results in short-stature adults compared with the predicted heights. Pubertal development tends to be ...
Differential diagnosis Graves-Basedow disease Abadie's sign of exophthalmic goiter is a medical sign characterized by spasm of the levator palpebrae superioris muscle with retraction of the upper lid (so that sclera is visible above cornea ) seen in Graves-Basedow disease which, together with exophthalmos causes the bulging eyes appearance.
Neuro-ophthalmologic examination showing ophthalmoplegia affecting the left eye in a patient with Tolosa–Hunt syndrome.The central image represents forward gaze, and each image around it represents gaze in that direction (for example, in the upper left image, the patient looks up and right; the left eye is unable to accomplish this movement).
Graves' ophthalmopathy, also known as thyroid eye disease (TED), is an autoimmune inflammatory disorder of the orbit and periorbital tissues, characterized by upper eyelid retraction, lid lag, swelling, redness (), conjunctivitis, and bulging eyes (exophthalmos). [1]