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Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
Common side effects include movement problems, sleepiness, dry mouth, low blood pressure upon standing, and increased weight. [6] Serious side effects may include the potentially permanent movement disorder tardive dyskinesia , neuroleptic malignant syndrome , severe lowering of the seizure threshold , and low white blood cell levels . [ 6 ]
The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. [4] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people. [8] [9]
Vomiting is a common condition affecting about 50% of pregnant women, with another 25% having nausea. [48] However, the incidence of HG is only 0.3–1.5%. [ 4 ] After preterm labor, hyperemesis gravidarum is the second most common reason for hospital admission during the first half of pregnancy. [ 16 ]
Gastrointestinal infections (37%) and food poisoning are the two most common causes of acute nausea and vomiting. [1] Side effects from medications (3%) and pregnancy are also relatively frequent. [1] There are many causes of chronic nausea. [1] Nausea and vomiting remain undiagnosed in 10% of the cases.
An estimated 20% (or one in five people) taking Ozempic experience nausea as a side effect. Since it’s so common, doctors who prescribe these drugs have become pros at helping patients treat it.
Serious side effects may include movement disorders including tardive dyskinesia and neuroleptic malignant syndrome. [6] Use in pregnancy and breastfeeding is generally not recommended. [ 10 ] It is a typical antipsychotic which is believed to work by reducing the action of dopamine in the brain.
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