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Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
Universal adaptive strategy theory (UAST) is an evolutionary theory developed by J. Philip Grime in collaboration with Simon Pierce describing the general limits to ecology and evolution based on the trade-off that organisms face when the resources they gain from the environment are allocated between either growth, maintenance or regeneration ...
Metaplasia occurs when a cell of a certain type is replaced by another cell type, which may be less differentiated. It is a reversible process thought to be caused by stem cell reprogramming. Stem cells are found in epithelia and embryonic mesenchyme of connective tissue. A prominent example of metaplasia involves the changes associated with ...
Many aspects of an animal or plant can be correctly called adaptations, though there are always some features whose function remains in doubt. By using the term adaptation for the evolutionary process, and adaptive trait for the bodily part or function (the product), one may distinguish the two different senses of the word. [14] [15] [16] [17]
The study of complex adaptive systems, a subset of nonlinear dynamical systems, [6] is an interdisciplinary matter that attempts to blend insights from the natural and social sciences to develop system-level models and insights that allow for heterogeneous agents, phase transition, and emergent behavior. [7]
The movement of phospholipids, even those located in the outer leaflet of the membrane, is regulated by the actin-based membrane skeleton meshwork.Which is surprising, because the membrane skeleton is located on the cytoplasmic surface of the plasma membrane, and cannot directly interact with the phospholipids located in the outer leaflet of the plasma membrane.
Spike times and subthreshold voltage of cortical neuron models can be predicted by generalized integrate-and-fire models such as the adaptive integrate-and-fire model, the adaptive exponential integrate-and-fire model, or the spike response model. In the example here, adaptation is implemented by a dynamic threshold which increases after each ...
Phenotypic plasticity refers to some of the changes in an organism's behavior, morphology and physiology in response to a unique environment. [1] [2] Fundamental to the way in which organisms cope with environmental variation, phenotypic plasticity encompasses all types of environmentally induced changes (e.g. morphological, physiological, behavioural, phenological) that may or may not be ...