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Third-generation cephalosporins have been used to treat gonorrhoea since 2007, but resistant strains have emerged. As of 2010, the recommended treatment is a single 250 mg intramuscular injection of ceftriaxone , sometimes in combination with azithromycin or doxycycline .
Amoxicillin is an antibiotic medication belonging to the aminopenicillin class of the penicillin family. The drug is used to treat bacterial infections [ 9 ] such as middle ear infection , strep throat , pneumonia , skin infections , odontogenic infections , and urinary tract infections . [ 9 ]
Within N. gonorrhoeae, genes exist that confer resistance to every single antibiotic used to cure gonorrhea, but thus far they do not coexist within a single gonococcus. However, because of N. gonorrhoeae ' s high affinity for horizontal gene transfer, antibiotic-resistant gonorrhea is seen as an emerging public health threat. [85]
Antibiotics are used to treat gonorrhea infections. As of 2016, both ceftriaxone by injection and azithromycin by mouth are most effective. [ 4 ] [ 57 ] [ 58 ] [ 59 ] However, due to increasing rates of antibiotic resistance , local susceptibility patterns must be taken into account when deciding on treatment.
The Canadian report called antibiotic-resistant gonorrhea “a serious public health threat” and said the STI’s ability to withstand two antibiotics used to treat it, ceftriaxone and ...
occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate, and piperacillin-tazobactam (not all vancomycin-resistant Enterococcus isolates are resistant to penicillin and ampicillin) occasionally doxycycline and minocycline
A study out of the University of York shows that carbon monoxide-releasing molecules could be the key to developing a new antibiotic to treat gonorrhea.
However, across the spectrum of dosage of amoxicillin-clavulanate combination, the dose of clavulanate is constant at 125 mg, whereas the dose of amoxicillin varies at 250 mg, 500 mg and 875 mg. Thus the use of low-dose amoxicillin-clavulanate in combination with meropenem may be used in part of a treatment regimen for drug-resistant TB and ...