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CML is more common in males than in females (male to female ratio of 1.4:1) and appears more commonly in the elderly with a median age at diagnosis of 65 years. [5] Exposure to ionising radiation appears to be a risk factor, based on a 50 fold higher incidence of CML in Hiroshima and Nagasaki nuclear bombing survivors. [ 5 ]
Specialty: Hematology and oncology: Symptoms: Bleeding, bruising, fatigue, fever, increased risk of infections [2] Usual onset: All ages, [3] most common in 60s and 70s. [4] It is the most common malignant cancer in children, but the cure rates are also higher for them.
Chronic myelogenous leukemia Chronic lymphocytic leukemia , including Hairy cell leukemia Myeloproliferative neoplasms including polycythemia vera , essential thrombocythemia , primary myelofibrosis , chronic neutrophilic leukemia , and chronic eosinophilic leukemia .
Accelerated phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which the disease ... Common symptoms include fever, bone pain, and ...
The prognosis depends on the type of cells affected, the number of blasts in the bone marrow or blood, and the changes present in the chromosomes of the affected cells. [3] The average survival time following diagnosis is 2.5 years. [4] MDS was first recognized in the early 1900s; [5] it came to be called myelodysplastic syndrome in 1976. [5]
CLL/SLL is the most common adult leukemia in Western countries, accounting for 1.2% of the new cancers diagnosed each year in the United States. It usually occurs in older adults (median age at diagnosis 70) and follows an indolent course over many years. [11] About 1-10% of CLL/SLLs develop a Richter's transformation at a rate of 0.5–1% per ...
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In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. In CMML, there are increased numbers of monocytes and immature blood cells ( blasts ) in the peripheral blood and bone marrow, as well as abnormal looking cells ( dysplasia ) in at least one type of blood cell.
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