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Metabolic bone disease is an abnormality of bones caused by a broad spectrum of disorders. Most commonly these disorders are caused by deficiencies of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated.
It represents a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination of the following: [1] [2] Abnormalities of calcium, phosphorus , parathyroid hormone, or vitamin D metabolism; Abnormalities in bone turnover, mineralization, volume, linear growth, or strength
The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is a resource for scientists and students seeking an overview of the bone and mineral field and for clinicians who see patients with disorders of bone and mineral metabolism. The text provides valuable information on the symptoms, pathophysiology, diagnosis, and ...
On the other hand, CKD-MBD is defined as a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination of: 1) abnormalities of calcium, phosphorus, PTH, or vitamin D metabolism; 2) abnormalities in bone turnover, mineralization, volume, linear growth, or strength (renal osteodystrophy); and
Mucopolysaccharidoses are a group of metabolic disorders caused by the absence or malfunctioning of lysosomal enzymes needed to break down molecules called glycosaminoglycans (GAGs). These long chains of sugar carbohydrates occur within the cells that help build bone, cartilage, tendons, corneas, skin and connective tissue.
Download as PDF; Printable version; In other projects ... Bone disease refers to the medical ... Osteochondrodysplasia is a general term for a disorder of the ...
Generally, diseases outlined within the ICD-10 codes E70-E90 within Chapter IV: Endocrine, nutritional and metabolic diseases should be included in this category. The main article for this category is Metabolic disorders .
Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. The impairment of bone metabolism causes inadequate bone mineralization.