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From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [117] and $13 billion a year at its peak, [118] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years." [117]
There is some evidence that appropriate use of statin medications in people with chronic kidney disease who do not require dialysis may reduce mortality and the incidence of major cardiac events by up to 20% and are not that likely to increase the risk of stroke or kidney failure. [16] Asthma. Statins have been identified as having a possible ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, ... such as kidney disease and obesity. ... Up to 60% off must-have brands. AOL.
Other statins have a small risk of 0.44 cases per 10 000 person-years. [9] Previous chronic kidney disease and hypothyroidism increase the risk of myopathy due to statins. It is also more common in the elderly, those who are severely disabled, and when statins are used in combination with particular other medicines, such as ciclosporin. [14] [9]
For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention. The sooner kidney dysfunction is diagnosed and treated the greater odds of preserving remaining nephrons, and preventing the need for dialysis.
The National Kidney Foundation notes that kidney disease can happen at any age but is more common in people over the age of 60. ... kidney functioning before he sewed me up. It started working the ...
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood).
In people aged under 50 years, more men than women have hypertension, [10] and in ages above 50 years the prevalence of hypertension is the same in men and women. [10] In ages above 65 years, more women than men have hypertension. [7] Hypertension becomes more common with age. [5] Hypertension is common in high, medium, and low-income countries.
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