Search results
Results from the WOW.Com Content Network
Glomerulonephrosis is a non-inflammatory disease of the kidney presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome. The nephron is the functional unit of the kidney and it contains the glomerulus, which acts as a filter for blood to retain proteins and blood lipids.
Mesangial proliferative glomerulonephritis often presents with hematuria (gross or microscopic) or nephrotic syndrome. [2] Presentation can also include asymptomatic proteinuria. [2] These presenting symptoms are relatively non-specific and are often seen in other glomerular disorders.
A meta-analysis of four randomized controlled trials comparing treatments of membranous nephropathy showed that regimes comprising chlorambucil or cyclophosphamide, either alone or with steroids, were more effective than symptomatic treatment or treatment with steroids alone in inducing remission of the nephrotic syndrome. [citation needed]
Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney that is characterized by a rapid loss of kidney function, [4] [5] (usually a 50% decline in the glomerular filtration rate (GFR) within 3 months) [5] with glomerular crescent formation seen in at least 50% [5] or 75% [4] of glomeruli seen on kidney biopsies.
Nephritis represents the ninth-most-common cause of death among all women in the US (and the fifth leading cause among non-Hispanic black women). [ 19 ] Worldwide, the highest rates [ clarification needed ] of nephritis are 50–55% for African or Asian descent followed by Hispanic at 43% and Caucasian at 17%.
Symptoms can be caused directly from DPGN or from a different disease that is causing DPGN. Many of the symptoms, like edema and hypertension, occur due to the decrease in glomerular filtration rate. [3] Patients can experience general systemic symptoms including fatigue, vomiting, nausea. These would all indicate uremia. [4]
This constellation of symptoms contrasts with the classical presentation of nephrotic syndrome (excessive proteinuria >3.5 g/day, low plasma albumin levels (hypoalbuminemia) <3 g/L, generalized edema, and hyperlipidemia). [8] [10] Signs and symptoms that are consistent with nephritic syndrome include: Hematuria (red blood cells in the urine) [11]
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine , low blood albumin levels , high blood lipids , and significant swelling . Other symptoms may include weight gain, feeling tired, and foamy urine.