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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Common adverse drug reactions (≥1% of those treated with the drug) associated with systemic metronidazole therapy include: nausea, diarrhea, weight loss, abdominal pain, vomiting, headache, dizziness, and metallic taste in the mouth. Intravenous administration is commonly associated with thrombophlebitis.
Symptoms of liver damage include anorexia, dark urine, jaundice, tender abdomen and pruritus. [39] To assess the liver function, ALT/AST should be closely monitored. [ 39 ] This antibiotic may also induce rare side effects in the cardiovascular system, such as QT prolongation , which may precipitate arrhythmia .
Symptoms from a lower urinary tract infection include suprapubic pain, painful urination , frequency and urgency of urination despite having an empty bladder. [1] Symptoms of a kidney infection, on the other hand, are more systemic and include fever or flank pain usually in addition to the symptoms of a lower UTI. [ 10 ]
[70] [71] A 2019 review found that this type of therapy may reduce symptoms of CPPS without side effects, but may not improve sexual problems. [64] 5-alpha reductase inhibitors probably help to reduce prostatitis symptoms in men with CPSS and don't appear to cause more side effects than when a placebo is taken. [64]
The use of topical antibiotics to treat surgical wounds does not reduce infection rates in comparison with non-antibiotic ointment or no ointment at all. [18] The use of doxycycline in acne vulgaris has been associated with increased risk of Crohn's disease. [19] The use of minocycline in acne vulgaris has been associated with skin and gut ...
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It is susceptible to the antibiotic clindamycin. [8] Growth of "fried egg" colonies on glucose agar medium within 24–48 hours is a characteristic of Mycoplasma hominis. [citation needed] This pathogen may latently infect the chorionic villi tissues of pregnant women, thereby impacting pregnancy outcome. [9]
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