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  2. Pyruvate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase

    Decreased activity of mitochondrial PDH with age has been shown in the heart as well as in certain regions of the brain (the striatum and brainstem). [6] Pyruvate dehydrogenase (PDH) deficiency is a congenital degenerative metabolic disease resulting from a mutation of the pyruvate dehydrogenase complex (PDC) located on the X chromosome.

  3. Pyruvate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase...

    The neurological form of PDCD contributes to hypotonia, poor feeding, lethargy and structural abnormalities in the brain. [4] Patients may develop seizures and/or neuropathological spasms. These presentations of the disease usually progress to mental retardation , microcephaly , blindness , and spasticity.

  4. Pyruvate dehydrogenase complex - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase_complex

    Pymol-generated image of E1 subunit of pyruvate dehydrogenase complex in E. Coli. The E1 subunit, called the pyruvate dehydrogenase subunit, is either a homodimer (comprising two “α” chains, e.g. in Escherichia coli) or a heterotetramer of two different chains (two “α” and two “β” chains).

  5. Neuroendocrinology - Wikipedia

    en.wikipedia.org/wiki/Neuroendocrinology

    Neuroendocrinology arose from the recognition that the brain, especially the hypothalamus, controls secretion of pituitary gland hormones, and has subsequently expanded to investigate numerous interconnections of the endocrine and nervous systems. The endocrine system consists of numerous glands throughout the body that produce and secrete ...

  6. Neural top–down control of physiology - Wikipedia

    en.wikipedia.org/wiki/Neural_top–down_control...

    Neural top–down control of physiology concerns the direct regulation by the brain of physiological functions (in addition to smooth muscle and glandular ones). Cellular functions include the immune system’s production of T-lymphocytes and antibodies, and nonimmune related homeostatic functions such as liver gluconeogenesis, sodium reabsorption, osmoregulation, and brown adipose tissue ...

  7. PDH - Wikipedia

    en.wikipedia.org/wiki/PDH

    PDH may refer to: Angiotensin-converting enzyme, an enzyme; Plesiochronous digital hierarchy, in telecommunications networks; Pound–Drever–Hall technique for stabilizing a laser's output; Pyranose dehydrogenase (acceptor), an enzyme; Pyruvate dehydrogenase, an enzyme

  8. Paraventricular nucleus of hypothalamus - Wikipedia

    en.wikipedia.org/wiki/Paraventricular_nucleus_of...

    The PVN contains magnocellular neurosecretory cells whose axons extend into the posterior pituitary, parvocellular neurosecretory cells that project to the median eminence, ultimately signalling to the anterior pituitary, and several populations of other cells that project to many different brain regions including parvocellular preautonomic cells that project to the brainstem and spinal cord.

  9. Development of the nervous system in humans - Wikipedia

    en.wikipedia.org/wiki/Development_of_the_nervous...

    Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially, the extent and speed. The nervous system continues to develop during adulthood until brain death. [additional citation(s) needed] For example: physical exercise has neurobiological effects

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