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Ribociclib, sold under the brand name Kisqali, is a medication used for the treatment of certain kinds of breast cancer. [4] Ribociclib is a kinase inhibitor. [ 4 ] It was developed by Novartis and Astex Pharmaceuticals .
“Hormones can certainly contribute to weight gain, but they are not the only reason for weight gain,” Dr. Ali says. “Diet and exercise play a role, too.” “Diet and exercise play a role ...
Weight fluctuations of five pounds are more are uncommon among men. Experts explain common sudden weight gain causes, what to do, and when to see a doctor. 12 Common Causes of Sudden Weight Gain
Another remaining question surrounding CDK inhibitors as a therapy is if certain cancers will evade or be resistant to treatment. One study showed that 20% of the patients being treated for metastatic ER+ HER2-breast cancer did not respond at all to treatment with a CDK4/6 inhibitor due to preexisting mutations allowing the cancer cells to continue proliferating despite treatment with the drug ...
Bloating is a feeling of tightness, pressure or fullness in your stomach, according to the Cleveland Clinic. It can also come with a swollen (aka distended) stomach, but it doesn't in all cases ...
Excess dietary fiber intake is a known cause of belching, gas and bloating. Many vegetables are known to cause bloating due to high levels of fiber and undigestible sugars such as raffinose (e.g., beans, cabbage, broccoli). [12] There are many individuals who are unable to tolerate dairy products because of lactose intolerance. Such foods ...
The FDA expanded the approval of Kisqali, a drug for metastatic breast cancer, to treat patients with earlier stage cancer, Novartis said. ... It may also cause fewer side effects, Teplinksy said ...
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.