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Inside the test chamber, during the Anti-Mass Spectrometer test that sparks the Resonance Cascade disaster. In "Black Mesa Inbound", the player controls Gordon Freeman as he enters the facility on a monorail. After noticing the G-Man on a different train, Gordon departs and enters the Anomalous Materials Lab. He explores the area, donning his ...
This method of injection works well with pulsed sources such as MALDI but cannot be interfaced to continuous ion sources like electrospray. All commercial Orbitrap mass spectrometers utilize a curved linear trap for ion injection (C-trap). By rapidly ramping down trapping RF voltages and applying DC gradients across the C-trap, ions can be ...
Ion mobility spectrometry-mass spectrometry (IMS/MS or IMMS) is a technique where ions are first separated by drift time through some neutral gas under an applied electrical potential gradient before being introduced into a mass spectrometer. [43] Drift time is a measure of the collisional cross section relative to the charge of the ion.
The combination of mass spectrometry and IRMPD with tunable lasers (IR ion spectroscopy) is increasingly recognized as a powerful tool for small-molecule identification. [8] Examples are metabomics, where biomarkers are identified in body fluids (urine, blood, cerebrospinal) [ 9 ] and forensic sciences, where isomeric designer drugs were ...
A linear ion trap component of a mass spectrometer. An ion trap mass spectrometer may incorporate a Penning trap (Fourier-transform ion cyclotron resonance), [12] Paul trap [13] or the Kingdon trap. [14] The Orbitrap, introduced in 2005, is based on the Kingdon trap. [15] Other types of mass spectrometers may also use a linear quadrupole ion ...
Mass spectrometry (MS) is an analytical technique that measures the mass-to-charge ratio (m/z) of charged particles (ions). Although there are many different kinds of mass spectrometers, all of them make use of electric or magnetic fields to manipulate the motion of ions produced from an analyte of interest and determine their m/z. [18]
The mass spectrometry analysis, however, takes place at high vacuum condition. Therefore, ions entering the mass spectrometer, first go through a source - to - analyzer interface (vacuum interface), which was designed in order to bridge the atmospheric pressure region to the mass spectrometer vacuum. It also minimizes spectrometer contamination.
A TOF mass spectrometer can also have a low-duty cycle when coupled with a continuous ion source. Combining an ion trap with a TOF mass analyzer can improve the duty cycle. Both 3D and linear traps have been combined with TOF mass analyzers. A trap can also add MSn capabilities to the system. [1]