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Cutaneous T-cell lymphoma (CTCL) is a class of non-Hodgkin lymphoma, which is a type of cancer of the immune system. Unlike most non-Hodgkin lymphomas (which are generally B-cell -related), CTCL is caused by a mutation of T cells .
Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, [1] is the most common form of cutaneous T-cell lymphoma. It generally affects the skin, but may progress internally over time. Symptoms include rash, tumors, skin lesions, and itchy skin. While the cause remains unclear, most cases are not hereditary.
Cutaneous lymphoma, also known as lymphoma cutis, is when lymphoma involves the skin. [1] It is characterized by a proliferation of lymphoid tissue. [2] There are two main classes of lymphomas that affect the skin: [citation needed] Cutaneous T-cell lymphoma; Cutaneous B-cell lymphoma
In cutaneous lymphoma, a lymphoma of the skin, the itching can be caused by a rash, she explains, but in other types, chemicals known as cytokines are released by the body as an autoimmune ...
It is to be distinguished from two other primary cutaneous lymphomas that involve B-cells, primary cutaneous follicle center lymphoma (PCFCL) and primary cutaneous marginal zone lymphoma (PCMZL), [8] as well as from a B-cell lymphoma that at diagnosis may appear to be limited to the skin but often is a systemic disease affecting numerous organs ...
The "primary" used to designate cutaneous lymphomas indicates that the lymphoma was first diagnosed as limited to the skin and there was no evidence of spread to extracutaneous tissues for 6 months after the diagnosis was first made. [4]) In 2022, however, the International Consensus Classification (ICC) group of experts in various medical ...
Primary cutaneous diffuse large B-cell lymphoma, leg type; Because recent studies had shown that primary cutaneous marginal zone lymphoma, which was formerly classified as a subtype of the MALT lymphomas: a) has a distinct microscopic histology and gene expression profile; b) spreads to extracutaneous tissue in only 4 to 8.5% of cases; c) has a ...
T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. [1] Lymphoma arises mainly from the uncontrolled proliferation of lymphocytes, such as T-cells, and can become cancerous. [2] T-cell lymphoma is categorized under Non-Hodgkin lymphoma (NHL) and represents less than 15% of all Non-Hodgkin's diseases in the category. [3]
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