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The nasolabial folds, commonly known as "smile lines" [1] or "laugh lines", [2] [self-published source] are facial features. They are the two skin folds that run from each side of the nose to the corners of the mouth. They are defined by facial structures that support the buccal fat pad. [3] They separate the cheeks from the upper lip.
Adenoma sebaceum, also known as facial angiofibroma is a misnamed cutaneous disorder consisting of angiofibromas that begin in childhood (generally present between 2–5 years of age) and appear clinically as red papules on the face especially on the nasolabial folds, cheek and chin, [1]: 195 often misidentified as acne not responding to treatment.
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A malar rash of lupus is red or purplish and mildly scaly. It has the characteristic shape of a butterfly, and involves the bridge of the nose. Notably, the rash spares the nasolabial folds of the face, which contributes to its characteristic appearance. It is usually macular with sharp edges, and not itchy.
Each of these treatment modalities have primary concerns that they address. For example, botulinum injections paralyze facial muscles. This prevents muscle contraction and subsequent wrinkle formation. [15] Injectable fillers are often used in the nasolabial fold to increase volume and minimize the appearance of sagging or wrinkling.
This nasolabial cyst, also known as a nasoalveolar cyst, is located superficially in the soft tissues of the upper lip. Unlike most of the other developmental cysts , the nasolabial cyst is an example of an extraosseous cyst, one that occurs outside of bone.
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
Congenital hypertrophy of the lateral fold of the hallux; Congenital lip pit (congenital sinus of the lower lip, lip sinus, midline sinus of the upper lip) Congenital malformations of the dermatoglyphs; Congenital smooth muscle hamartoma; Cystic lymphatic malformation; Dermoid cyst; Diffuse neonatal hemangiomatosis; Encephalocele