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Immunoreactive axonal profiles are observed as either granular (B, G, H) or more elongated, fusiform (F) swellings in the corpus callosum and the brain stem (H) at 24h post traumatic brain injury. Example of APP immunoreactive neurons (arrow heads) observed in the cortex underneath the impact site (E, G). No APP staining was observed in healthy ...
The condition can be diagnosed and monitored with brain sonography and CT/MRI. These tests and a good medical history can help to identify external hydrocephalus from similar conditions: subdural hemorrhages or symptomatic chronic extra-axial fluid collections which are accompanied by vomiting, headaches, and seizures. [58] [59]
Symptoms of brain injuries can also be influenced by the location of the injury and as a result, impairments are specific to the part of the brain affected. Lesion size is correlated with severity, recovery, and comprehension. [16] Brain injuries often create impairment or disability that can vary greatly in severity. Studies show there is a ...
Hemorrhagic parenchymal contusions and cerebral microhemorrhages are examples of traumatic intra-axial bleeds. [3] Extra-axial hemorrhage, bleeding that occurs within the skull but outside of the brain tissue, falls into three subtypes: epidural hematoma, subdural hematoma, and subarachnoid hemorrhage. [3]
The outlook for someone with lateral medullary syndrome depends upon the size and location of the area of the brain stem damaged by the stroke. [2] Some individuals may see a decrease in their symptoms within weeks or months, while others may be left with significant neurological disabilities for years after the initial symptoms appear. [4]
The brain damage caused by radiation depends on where the brain tumor is located, the amount of radiation used, and the duration of the treatment. Radiosurgery can also lead to tissue damage that results in about 1 in 20 patients requiring a second operation to remove the damaged tissue. [27] [28]
Subdural hygromas require two conditions in order to occur. First, there must be a separation in the layers of the Meninges of the brain. Second, the resulting subdural space that occurs from the separation of layers must remain uncompressed in order for CSF to accumulate in the subdural space, resulting in the hygroma. [1]
Lesion network mapping is a neuroimaging technique that analyzes the connectivity pattern of brain lesions to identify neuroanatomic correlates of symptoms. [1] [2] [3] The technique was developed by Michael D. Fox and Aaron Boes to understand the network anatomy of lesion induced neurologic and psychiatric symptoms that can not be explained by focal anatomic localization.