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  2. Orexin antagonist - Wikipedia

    en.wikipedia.org/wiki/Orexin_antagonist

    An orexin receptor antagonist, or orexin antagonist, is a drug that inhibits the effect of orexin by acting as a receptor antagonist of one (selective orexin receptor antagonist or SORA) or both (dual orexin receptor antagonis or DORA) of the orexin receptors, OX 1 and OX 2. [1] Medical applications include treatment of sleep disorders such as ...

  3. What is gabapentin? Here's why it's so controversial. - AOL

    www.aol.com/gabapentin-heres-why-controversial...

    Gabapentin is a prescription medication that was approved by the U.S. Food and Drug Administration in 1993 as a treatment for epilepsy. It works by binding to a type of calcium channel in nerve ...

  4. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    There are two drug-binding α 2 δ subunits, α 2 δ-1 and α 2 δ-2, and most gabapentinoids show similar affinity for (and hence lack of selectivity between) these two sites. [1] In most cases, gabapentinoid drugs do not seem to directly alter the action of VGCC and instead reduce the release of certain excitatory neurotransmitters. [2 ...

  5. What is Sleep Apnea? Symptoms & Treatment Options - AOL

    www.aol.com/sleep-apnea-symptoms-treatment...

    Sleep apnea is a common sleep disorder that affects more than 20 percent of people in the United States. It happens when your breathing temporarily stops while you sleep. Depending on the severity ...

  6. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon has been evaluated for potential drug interactions with the following medications and showed no significant effects: omeprazole, theophylline, dextromethorphan, and midazolam, digoxin and warfarin. There were no clinically meaningful effects when ramelteon was coadministered with any of these drugs. [medical citation needed]

  7. FDA approves weight-loss drug Zepbound for obstructive sleep ...

    www.aol.com/fda-approves-weight-loss-drug...

    The US Food and Drug Administration on Friday approved the first prescription medicine for obstructive sleep apnea: the weight-loss drug Zepbound.

  8. Lemborexant - Wikipedia

    en.wikipedia.org/wiki/Lemborexant

    Lemborexant is used in the treatment of insomnia in adults. [3]A major systematic review and network meta-analysis of medications for the treatment of insomnia published in 2022 found that lemborexant had an effect size (standardized mean difference (SMD)) against placebo for treatment of insomnia at 4 weeks of 0.36 (95% CI Tooltip confidence interval 0.08 to 0.63) and at 3 months of 0.41 (95% ...

  9. Weight-loss drug Zepbound resolves sleep apnea in up to 52% ...

    www.aol.com/news/weight-loss-drug-zepbound...

    Eli Lilly on Friday said its popular weight-loss drug Zepbound helped resolve moderate to severe obstructive sleep apnea in up to 52% of patients in two late-stage trials. U.S.-based Lilly and ...

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