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After seroconversion, sufficient concentration of the specific antibody exists in the blood, and the serological assay will detect the antibody. The individual is now seropositive for the antibody. [14] During seroconversion, when the amounts of antibody and antigen are very similar, it may not be possible to detect free antigen or free ...
In immunofluorescence, the level of autoantibodies is reported as a titre. This is the highest dilution of the serum at which autoantibodies are still detectable. Positive autoantibody titres at a dilution equal to or greater than 1:160 are usually considered as clinically significant.
The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity. HIV/AIDS [ edit ]
A viral titer is the lowest concentration of a virus that still infects cells. To determine the titer, several dilutions are prepared, such as 10 −1, 10 −2, 10 −3, ... 10 −8. [1] The titer of a fat is the temperature, in degrees Celsius, at which it solidifies. [4] The higher the titer, the harder the fat.
Serology is the scientific study of serum and other body fluids.In practice, the term usually refers to the diagnostic identification of antibodies in the serum. [1] Such antibodies are typically formed in response to an infection (against a given microorganism), [2] against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in ...
Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]
Two serotypes 1a and 1b with antigens 2a and 2b on surface, which are recognized by two distinct antibodies, 3a and 3b, respectively. A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals.
Seroconversion is defined as an increase in HI (Hemagglutination-Inhibition) antibody titer of at least 4-fold, with a minimum post-vaccination HI titer of 1:40. I believe this refers to results from a Viral Hemagglutination Assay