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Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
The pelagic food web, showing the central involvement of marine microorganisms in how the ocean imports nutrients from and then exports them back to the atmosphere and ocean floor. A marine food web is a food web of marine life. At the base of the ocean food web are single-celled algae and other plant-like organisms known as phytoplankton.
A freshwater aquatic food web. The blue arrows show a complete food chain (algae → daphnia → gizzard shad → largemouth bass → great blue heron). A food web is the natural interconnection of food chains and a graphical representation of what-eats-what in an ecological community.
Category: Orexin antagonists. 7 languages. ... This list may not reflect recent changes. ...
Both orexin receptors exhibit a similar pharmacology – the 2 orexin peptides, orexin-A and orexin-B, bind to both receptors and, in each case, agonist binding results in an increase in intracellular calcium levels. However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors ...
Orexin receptor antagonists can affect the reward system and produce drug-liking responses in humans. [ 27 ] [ 16 ] Daridorexant at a dose of 50 mg (the maximum recommended dose) showed significantly greater drug liking than placebo but significantly less drug liking than zolpidem (30 mg) and suvorexant (150 mg) in recreational sedative drug users.
Pages in category "Orexin receptor agonists" The following 5 pages are in this category, out of 5 total. This list may not reflect recent changes. D. Danavorexton; F.
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